After administering albuterol for acute bronchospasm, which sign would best indicate a positive clinical response?

• A. Worsened wheeze
• B. Decreased oxygen saturation
• C. Increased work of breathing
• D. Improved wheeze and air entry

Answer: (D)

Albuterol works by relaxing bronchial smooth muscle, opening the airways so air can move more freely. The best sign of a positive response is easier airflow demonstrated by improved air entry and a more favorable breath sound (improved wheeze) on auscultation. This shows the lungs are receiving air more effectively. Signs like a worse wheeze, lower oxygen saturation, or increased work of breathing suggest the bronchospasm is not adequately relieved and the patient remains in distress.